To alleviate suffering & improve the quality of life of patients with incurable or intractable disorders & injury of the nervous system, by restoring functional abilities to a maximum possible, by extending a professional, holistic & caring manner, and to conduct basic & clinical research by constant work on innovation & development, so that the best therapeutic strategies can be evolved.
In the past donated organs were transplanted to replace the diseased or failed organs in the recipients. Soon the number of recipients exceeded the number of donated. To overcome this demand, cell therapy offered the possibility of replacement of the damaged cells of tissue with new cells. Stem cell infusion helps to treat a plethora of conditions including cerebral palsy, spinal cord injury, intellectual disability, and other neurodegenerative syndromes as well.
Stem cells have the potential to develop into different cells of the tissues (of the body) and the ability of self-renewal. When serving as a repair system, the stem cells divide without limit as long as the person is alive. As they divide, they remain as stem cells or develop into cells with more specialized functions, like a brain cell or a muscle cell.
Stem cells, from different sources, have three common properties: They can grow into specialized cell types such as nerve cells, muscle cells, and blood cells.
Impairments linked to neuromuscular conditions are usually irreversible due to inadequate cell regeneration or impaired cells in the central nervous system. It was observed that the cellular characteristics of autologous stem cells had the capability of treating major neurological disorders without incurring any side effects. With their neurotrophic properties, self-renewal & differentiation capacity, and immune modulation effects, the bone marrow-derived stem cells are considered as a promising candidate for treating disorders related to the nervous system.
For cell treatment, bone marrow derived mesenchymal stem cells are isolated from the marrow tissue (extracted from the patient’s hip bone) in an expedited, painless and safe way. By centrifugation procedure, a sufficient number of stem cells are separated from the unwanted tissue within a few hours. These injectable stem cells are infused intrathecally into the spinal area or the damaged muscle points, as per the need of the patients.
These bone marrow-derived stem cells have many useful properties that lead to great clinical improvement in post-cell-based therapy. According to various clinical trials, treatment with bone marrow derived mesenchymal stem cells have shown improvement in patients with traumatic brain injury, spinal cord injury and other neurological disorders through axonal sprouting and remyelination, potential to replace/protect the damaged neurons/cells, and neovascularization.
How do the infused stem cells act? Once infused into the body,
– The infused stem cells journey toward the nervous system and blend into the neural circuits to mend or improve the disrupted synaptic transmission.
– Post infusion, improved neuropathological condition, upregulated Aß clearance and reduced deposition is detected within a short period.
– The infused stem cells reduce neuroinflammation and provide protective immunomodulatory effect.
– The stem cells secrete neurotrophic influence and nerve growth factors, bringing cognitive and memory improvement in patients.
Apart from encouraging effects, renewed brain plasticity is also observed in patients following intrathecal delivery of stem cells. With the new medical breakthrough in stem cell therapy, the treatment has become a highly sought-after curative. To know about the treatment efficacy, one must understand the efficiency of stem cells in terms of engraftment, migration, cytokines and growth factors. However, cell-based therapy is a promising contribution to regenerative medicine and has gained considerable clinical attention. Read more info on NeuroGen BSI.
Speech therapy also tackles problems that affect a child’s ability to eat. Many children with CP struggle to maintain a healthy weight because it’s hard to chew or swallow food. Oral motor exercises can improve the ability to chew and swallow food effectively. Speech therapists also work with other therapists. For example, a speech therapist and an occupational therapist can help children with drooling problems due to low muscle tone in the face and mouth. There are multiple surgical treatments that can help correct movement problems in children with cerebral palsy. However, parents should keep in mind that surgery isn’t right for every child with cerebral palsy. Surgery is most commonly prescribed for those with spastic cerebral palsy because their increased muscle tone can be reduced to relieve restricted movement. For example, a child who walks on their toes due to high muscle tone in their legs can have those muscles or tendons lengthened, allowing for more normal walking.
A few advices to help your child with autism: Common autism treatments include behavior therapy, speech-language therapy, play-based therapy, physical therapy, occupational therapy, and nutritional therapy. But keep in mind that the routine is important and the program should be designed in a way that can be sustained. You should think about what skills and behaviors are most essential and treat those first. It may not be possible to tackle everything at once. Caring for a child with ASD can demand a lot of energy and time. There may be days when you feel overwhelmed, stressed, or discouraged. Parenting isn’t ever easy, and raising a child with special needs is even more challenging. In order to be the best parent you can be, it’s essential that you take care of yourself. Don’t try to do everything on your own. You don’t have to! There are many places that families of children with ASD can turn to for advice, a helping hand, advocacy, and support.
A spinal cord injury is damage to the spinal cord. It’s an extremely serious type of physical trauma that’s likely to have a lasting and significant impact on most aspects of daily life. The spinal cord is a bundle of nerves and other tissue that the vertebrae of the spine contains and protects. The vertebrae are the bones stacked on top of each other that make up the spine. The spine contains many nerves, and extends from the brain’s base down the back, ending close to the buttocks.
Stem cells are those cells that can develop into any type of cells, such as liver, muscle, blood or other cells with specific functionality. Basically, stem cells are the basic cells of the human body, the “bricks” that make up life. They create our organs, tissues, blood and our immune system. Interestingly, however, most cells in our body can only give birth to cells of the same type (for example, blood cells produce blood cells, epidermal cells produce more skin cells, etc.). Stem cells, on the other hand, are unique cells that can give rise to several types of cells (a stem cell can create blood, kidney, heart or bones).
Stem cell therapy is the finest medical breakthrough in history. It has bagged the much acclaimed ‘Nobel Prize in Medicine’ in the year 2012. This miracle discovery, Stem Cell therapy, has leveraged and firmly positioned India in the field of medical science, worldwide. Stem cell therapy has changed the medical perception of ‘incurable neurological disorders’ and has broken all shackles. Regenerative medicine or stem cell therapy is one of the most promising branches of advanced medication. Its main objective is to restore organ and tissue function for patients with continual and persistent diseases. Over the years, scientists and surgeons have been using stem cell therapy to renew and repair tissues affected with age, disease and congenital defects. See more details at Stem Cell Therapy.